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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of uveal melanoma (UM)
ncRNA name hsa-miR-144
ncRNA Category miRNA
Disease name uveal melanoma (UM)
Species Homo sapiens
Tissues/Cell_line UM cell lines MUM-2B, C918, MUM-2C and OCM-1A; human melanocyte cell line D78
Methods qRT-PCR, CCK-8 assay, transfection, transwell assay, Western blot, luciferase reporter assay
Expression pattern down-regulated
Functional description miR-144 acts as a tumor suppressor in uveal melanoma, through inhibiting cell proliferation and migration.
PubMed ID 25961751
Year 2015
Title MiR-144 Inhibits Uveal Melanoma Cell Proliferation and Invasion by Regulating c-Met Expression.
Drug-related ncRNA NO

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